Kyle Lowry had 26 points and Serge Ibaka added 11 for the Raptors, who also won 12 straight at Air Canada Centre between January 18 and March 6, 2016.
Milwaukee came to the ACC fresh off a feat the Raptors couldn't achieve - beating the Oklahoma City Thunder on the road. Prior to the victory against the Thunder, the Bucks defeated the Minnesota Timberwolves 102-96, completing their largest comeback since 2013, fighting all the way back from 20-down in the third quarter.
DeRozan played perhaps his best defensive possession of the game on the final play, harassing Milwaukee's Eric Bledsoe until the buzzer went.
The Bucks' reserves inched their team into the lead inside the second quarter, despite a mesmerizing five-point, two-assist stretch from Toronto reserve point guard Delon Wright, including some flashy passes and a heads-up interception for a dunk.
DeMar DeRozan scored a franchise-record 52 points as the Raptors clipped the Bucks 131-127 in overtime in Toronto. So far this season, DeRozan is averaging 24.1 points, 4.3 rebounds and 4.9 assists.
Giannis Antetokounmpo added 26 points with nine rebounds and seven assists.
Getting familiar: After Monday's first meeting against the Bucks, the two teams will meet again on Friday, Jan. 5, this time in Milwaukee.
The Raptors (25-10) have quietly risen to second in the Eastern Conference.