Kasim Hill was 6 of 15 passing for 47 yards and a pick for the Terps (4-3, 2-2), who ran for just 68 yards after entering play averaging 245 a game on the ground. Purdue set a team record for points scored against the Buckeyes, besting the mark of 41 in 1967. The Buckeyes got the yards, but not the points.
Nelson, a defensive end, made it 23-0 Hawkeyes late in the third quarter by falling on a botched handoff from backup quarterback Tyrrell Pigrome in the end zone. That's largely a effect of how one-dimensional they have become. Haskins connected with Terry McLaurin on a 34-yard touchdown pass with four minutes to play for the Buckeyes' other touchdown.
Ohio State has a bye week to work on its problems before returning to action against Nebraska on November 3. Ohio State is now looking up at MI in the Big Ten East standings.
David Blough threw for 378 yards and 3 touchdowns, while DJ Knox ran for three scores. Clemson moves up to No. 2 in Ohio State's place and is followed by Notre Dame, LSU and MI. But Davon Hamilton got a roughing penalty, and Purdue capitalized for a touchdown.
Blough outplayed Heisman Trophy candidate Dwayne Haskins Jr. on a night the Buckeyes didn't reach the end zone until early in the fourth quarter. It was Blough's third straight 300-yard game and his fourth this season. But the game's first four possessions ended in punts.
The first of those came with the help of two 15-yard Purdue penalties. It was the second straight week they'd pulled one off in a game after scoring a touchdown on a double-reverse wide-receiver pass against IL.
Haskins wound up 49 of 73, shattering the single-game school records in both categories, and had 470 yards and two touchdowns and one interception. The Wolverines are in the midst of a three-game stretch against ranked opponents, having already defeated No. 15 Wisconsin and No. 24 Michigan State.
Ohio State had a chance to match Purdue's 98-yard drive when it drove from its 2 to the Purdue 16.
Knox added a second long touchdown later in the fourth quarter, making a man miss in the backfield and sprinting 40 yards untouched after that for his third touchdown of the game.
Purdue quickly drove deep into Ohio State territory in the final minute of the second quarter. Purdue hit paydirt on the next play on a Rondale Moore nine-yard TD catch.
He sent his field-goal unit out onto the field, but instead of going for three he called for a fake that worked to perfection.